Applied Mathematics

Computer Models provide new understanding of sickle cell disease

Mesoscopic Adaptive ResolutionSimulations developed by George Karniadakis and his research group provide new details of how sickle cell disease manifests inside red blood cells, which could provide help in developing new treatments.

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George Karniadakis' research group including Lu Lu, He Li, Xin Bian and Xuejin Li have published research which reveals a new understanding of the intracellular polymerization of sickle hemoglobin (Hbs).  

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Understanding the interactions between sickle cell fibers